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Author information Copyright and License information Middle eastern dating Sollentuna. Correspondence to: Murray A. Copyright notice. The publisher's final edited version of this article xhocolate available at Circ Heart Fail.

See other articles in PMC Sex o wap cite the published article. Abstract Background Randomized clinical trials have shown that chocolate intake reduces systolic and diastolic blood pressure and observational studies have found an inverse association between chocolate intake and cardiovascular disease. Methods and Results We conducted a prospective cohort study of Sweeden chocolate models, women 48—83 years old Sweeden chocolate models baseline diabetes or a history of HF or myocardial infarction who were participants in the Swedish Mammography Cohort.

Conclusions In this Sweeden chocolate models, moderate habitual chocolate intake was associated with a lower rate of HF hospitalization or death but the protective association was not observed with intake of one or more servings per day.

Diet Assessment The details of the food frequency questionnaire have been described previously Assessment of Other Covariates History of myocardial infarction MI at baseline and incident Chofolate during follow-up were assessed through the Swedish inpatient register. Follow-up and Ascertainment of HF Participants contributed follow-up Sweeden chocolate models from January 1, until the earliest of the following: Statistical Analysis Chocolate intake was categorized as no regular chocolate intake, 1—3 servings of chocolate per month, 1—2 servings Sweeden chocolate models week, 3—6 servings per week and one or more servings per day.

Open in a separate window. Prevention of heart failure: Heart disease and stroke statistics update: Cocoa Queens Kristinehamn escort service health: Br J Nutr.

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Chocolate and prevention of cardiovascular disease: Nutr Metab Lond ; 3: Effect of Cocoa Products on Blood Pressure: Systematic Sweeden chocolate models and Meta-Analysis. Am J Hypertens. Flavonoids, flavonoid-rich foods, and cardiovascular risk: Am J Clin Nutr. The emerging role of flavonoid-rich cocoa and chocolate in cardiovascular health and disease.

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Nutr Rev. Flavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in healthy adults. J Am Coll Nutr. Cocoa intake, blood pressure, and cardiovascular mortality: Arch Intern Med. Chocolate consumption in relation Sweeden chocolate models blood pressure and risk of cardiovascular disease in German adults.

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European heart journal. Flavonoid intake and cardiovascular disease mortality: Chocolate consumption and Sweeden chocolate models following a first acute myocardial infarction: J Intern Med. Long-term Swseden fish consumption and renal cell carcinoma incidence in women. Adiposity and incidence of heart failure hospitalization and mortality: Reproducibility and validity of major dietary patterns among Swedish women assessed with a food-frequency questionnaire.

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Pennington JAT. Willett WC. Nutritional Epidemiology. Oxford University Press; Sweeden chocolate models York: Reproducibility of the past year and historical self-administered total physical activity questionnaire among older moodels. Eur J Epidemiol. The Nation Board of Sweeden chocolate models and Welfare.

The Swedish Hospital Discharge Registry — The validity of a diagnosis of heart failure in a hospital discharge register. Eur J Heart Fail.

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Schafer JL. Analysis of Incomplete Multivariate Data. Plasma antioxidants from chocolate. Cocoa has more phenolic phytochemicals and a higher antioxidant capacity than teas and Adult free sex chat wine.

J Agric Food Chem. Effect of cocoa and tea intake on blood pressure: Hemodynamic and electrophysiologic effects of acute Sweeden chocolate models ingestion in young adults. The objective of this Sweeden chocolate models was to evaluate the association of chocolate consumption and heart failure in a large population of Swedish men.

We conducted a prospective cohort study of 31, men years old with no history of myocardial infarction, diabetes, or HF at baseline who were participants in the population-based Cohort of Swedish Men COSM Sweeden chocolate models. Chocolate consumption was assessed through a self-administrated food frequency questionnaire.

Participants were followed for HF hospitalization or mortality from January 1, to December 31, using record linkage to the Swedish inpatient and cause-of-death registries. Compared with subjects who reported no chocolate intake, the multivariable-adjusted rate ratio of Stars Kiruna road massage was 0.

In this large prospective cohort study, Sweeden chocolate models was a J-shaped relationship between chocolate consumption and HF incidence. Heart failure HF is a common cause of morbidity and mortality worldwide.

There are an estimated 5. With the increasing epidemic of HF, prevention is an important public health concern. Recent studies indicate that chocolate products Girl looking for boy in Skovde have beneficial effects on cardiovascular health. There is limited research on the association of chocolate consumption and heart failure. Therefore, we studied whether chocolate intake is associated with the risk of incident HF hospitalization or mortality in a population of Swedish men.

Cardiovascular and other diseases as well as surgeries and causes of death are identified by linkage to the National Inpatient and other registries at the Swedish Board of Health and Welfare. We excluded subjects with an incorrect Sweeden chocolate models incomplete national registration number, subjects with implausible reported energy intakes defined as more than 3 standard deviations from the mean value of the natural logarithm-transformed energy intakemissing data for more than half Sweeden chocolate models the food and beverage items, prior history of cancer, heart failure, prior myocardial infarction MI or diabetes, and those with missing information on chocolate consumption.

We excluded men with a history of MI or diabetes at baseline because these men were more likely to have received dietary counseling that could affect their Sweeden chocolate models of diet. After these exclusions, data on 31, participants were available for this analysis.

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Diet was assessed at baseline using a self-administered item, validated, food frequency questionnaire. We calculated total calorie intake based on the food frequency questionnaire.

The questionnaire Sweeden chocolate models items on education, cigarette smoking, frequency of consumption modele beer, wine, and spirits, family history of MI Sweeden chocolate models age 60, history of hypertension, and history of high cholesterol. History of MI at baseline was assessed through the Swedish inpatient register. We considered participants to have diabetes if they self-reported diabetes on the questionnaire or had been given any diagnosis of diabetes as recorded in the inpatient register.

I decided to make a super easy Swedish Cake Recipe for Easter. cake topping has a delicious combination of dark chocolate and blueberries. What I Eat In A Day As A Model | Fashion Week Preparation | Sanne Vloet. Museu de la Xocolata: Chocolate models - See traveler reviews, candid photos, and great deals for Barcelona, Spain, at TripAdvisor. For the Cox proportional hazard models, we chose covariates a priori . However, Swedish milk chocolate has a much higher cocoa content.

Physical activity was estimated by calculating metabolic equivalent in hours per day Sweeden chocolate models occupational Sweeden chocolate models activity, exercise, and sedentary behavior. Sweeden chocolate models Dietary Approaches to Stop Beautiful sex Sweeden DASH diet component score was calculated by ranking participants on intake of 1 fruits, 2 vegetables, 3 nuts and legumes, 4 low-fat dairy, 5 whole grains, 6 sodium, 7 sweetened beverages, and 8 red and processed meats.

Participants in the highest quintile of sodium, sweetened beverages, Swweeden red and processed meats Sweeen a score of 1 and those in the lowest quintile received a score of 5. The score for each component was summed to get the overall DASH score. Participants were then categorized into quartiles based on the DASH diet component score.

Individuals were observed from January 1,until the date of first hospital admission or death from heart failure HFdeath from other causes, or end of chcolate December 31,whichever came.

The results were averaged, and CIs and P values were calculated, accounting for the uncertainty in the imputed estimates. We reported baseline characteristics stratified by category of chocolate intake as mean and standard deviation Sweeden chocolate models as counts with proportions, as appropriate.

For the Cox proportional hazard Molndal transgender model, we chose covariates a priori Sweeden chocolate models we considered potential confounders on the basis of their association with both chocolate intake and development of HF.

In the first-stage model, we accounted for age by allowing the baseline rate to vary with age and adjusted for total energy intake continuous.

We conducted a Sweeden fuck massage for the quadratic component of trend by using the median-centered value for each level of chocolate intake Sweeden chocolate models determined the statistical significance of its squared value in Sweden multivariable model.

We performed multiple sensitivity analyses. We used both primary and secondary diagnosis of heart failure in our primary analysis which has shown validity in this population; 27 however, we also performed an analysis restricted to only primary choolate failure diagnosis. In order to assess whether the inverse association between chocolate intake and HF was mediated through history of hypertension, the rate ratios for chocolate intake in the multivariable-adjusted model were contrasted with the estimates for chocolate intake when Sweeden chocolate models indicator variable for hypertension was removed from the model.

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In order to further exclude patients at high risk, we performed an analysis excluding patients with hypertension and hyperlipidemia. We evaluated the effect of healthy diet on the Cheap call girl Stockholm with stratification by Sweeddn of DASH score.

Because milk consumption may inhibit the intestinal absorption of flavonoids, which may Sweeden chocolate models responsible for the cardio-protective effects of chocolate, 29 we calculated the product of indicator variables for chocolate intake and for milk consumption above or below the median and tested the significance Sweeden chocolate models this term in the multivariable model using a likelihood ratio test.

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Sweeden chocolate models We also examined whether the association varied by regular physical activity or BMI by performing a similar test of interaction using the product of Malaysian escort Enkoping variables for chocolate intake and the potential modifier.

We tested the proportional hazard assumption by including product terms of the predictors and the Sweecen of survival time, and found no significant violations. Statistical analyses were performed using SAS version 9. Median chocolate intake was Sweeden chocolate models per month. Compared to men reporting no chocolate intake, men who ate more Sweeden chocolate models had higher total daily energy intake, were more likely to be never smokers and have chkcolate education, and were less likely to be previously diagnosed with hypertension Chocolzte 1.

The results remained similar when we did not adjust for self-reported hypertension, and when we excluded patients with hypertension and hyperlipidemia. Stratification by smoking status or marital status did not materially change our results. The association between chocolate intake and HF was not modified by dairy intake, BMI or physical activity.

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Although consumption of biscuits, pastries, candy, ice cream, and chips and popcorn was strongly related to Gay in Norrkoping intake, it was not associated with HF incidence.

Chocolate has been shown to have multiple benefits to cardiovascular health, possibly mediated in part through their high concentration of plant-derived antioxidants called flavonoids.

Chocolate and cocoa flavonoids are associated with beneficial effects on endothelial function, 31 - 35 blood pressure, 710 - 14 platelets, 36 - 39 inflammation, Sweeden chocolate models41 high-density lipoprotein cholesterol, 42 insulin sensitivity, 43 and cardiometabolic makers. Multiple observational studies have demonstrated that chocolate intake is associated cuocolate clinical outcomes. Chocolate intake is associated with lower incidence of cyocolate 2245 and MI, 15 lower incidence of mortality from coronary heart disease, 56 and lower cardiac mortality in Sweeden chocolate models after their first MI.

Recent prospective studies have shown that moderate chocolate consumption is associated with Sweeden chocolate models lower incidence of HF Sweeden chocolate models a cohort of Swedish women 46 and a cohort of Sweeden latin male physicians.

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While the distribution of BMI and the results of this study are similar to our current study, we found no modification by BMI in our population. The reason for this discrepancy is not clear but may be related to differences in the type and flavonoid content of chocolate consumed in the Sweeden chocolate models compared to this Swedish cohort. The observed J-shaped relationship between chocolate consumption and heart failure may be due to the fact that we adjusted for Sweeden chocolate models Craigslist beaufort Enkoping personals caloric intake.

Therefore, it is possible that men who Molnlycke swinger hotel higher levels of chocolate on a daily basis are consuming Sweeden chocolate models calories from foods that may be salutary. Furthermore, as we were not not able to assess the exact consumption of cocoa flavonoids, it is unclear if a more linear relationship exists between flavonoids and heart failure.

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Chocolate Intake and Incidence of Heart Failure: Findings from the Cohort of Swedish Men

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